Nike co-founder Phil Knight and his wife, Penny, donated $25 million to the Providence Heart and Vascular Institute for patient care and cardiac research.
PayRange received $2.75 million from investors with connections to Google and PayPal, and from actor Jared Leto.
The Oregon bank wants to provide banking services to medical marijuana businesses in the state.
The high-profile bank will invest $50,000 in Greater Portland Inc., which aims to bolster the region's economy.
Oregon startups have raised $174 million to date, up from $162 million raised in 2013.