Home Back Issues March 2010 OSU professor develops a better anti-depressant

OSU professor develops a better anti-depressant

| Print |  Email
Articles - March 2010
Sunday, February 14, 2010

nexttest2In 2006, Oregon State University professor Jim White was deconstructing Cymbalta, a popular anti-depressant, when he discovered a hole in its molecular skeleton. White saw that as his opening for creating a new, more effective anti-depressant. Low levels of serotonin and norepinephrine — the neurotransmitters in the brain responsible for moods — cause depression. Ideally, anti-depressants stop serotonin and norepinephrine from leaving the brain and entering the blood stream. “To get the best effects, you need to have a balance of these two,” White says. “That hasn’t been achieved with any of the known anti-depressants.” His new compound showed strong interactions with both neurotransmitters when tested artificially and with rats. It could avoid common side effects and work more quickly than current drugs. “Our compound … is closer to the ‘holy grail’ of a perfectly balanced anti-depressant,” White says. He won’t know how effective the drug is until it’s tested on patients, but White and co-inventor and consultant David Wong are seeking a commercial partner to invest and develop the drug. White hopes the drug will be cheaper than other anti-depressants, or even generic versions. That, of course, depends on business, not chemistry.

AMANDA WALDROUPE
 

More Articles

Eking out a living

News
Tuesday, April 08, 2014
04.08.14 thumb ourtable-coopfarmsBY HANNAH WALLACE | OB BLOGGER

It may be obvious, but most farmers don’t make a lot of money. According to preliminary data from the 2012 Agriculture Census, 52% of America’s 2.1 million principal farm-operators don’t call farming their primary occupation. Farm cooperatives may offer a solution.


Read more...

Car ignition recalls and lean product design

Contributed Blogs
Friday, April 11, 2014
04.11.14 thumb gm-gettyTOM COX | OB BLOGGER

The auto industry is starting to share more costs across manufacturers for complex and challenging design work, like new transmission design, and certain new engine technologies. What we’re not yet seeing is wholesale outsourcing of “unavoidable waste” components to specialist companies.


Read more...

Downtime with Ron Green

March 2014
Tuesday, February 25, 2014
BY JESSICA RIDGWAY

Ron Green became president and CEO of Oregon Pacific Bank in August 2013.


Read more...

How to handle the unexpected

Contributed Blogs
Friday, March 28, 2014
03.28.14 thumb disasterBY TOM COX | OB BLOGGER

The next mysterious (or disastrous) event could be one that you or your team might suddenly need to respond to, probably under intense scrutiny.


Read more...

Making faces

News
Thursday, February 20, 2014
02.20.14 Thumbnail ModelsBY VIVIAN MCINERNY | OB BLOGGER

As retailers consolidate and newspapers fold, the business of modeling shifts to ad agencies, apparel companies and new media.


Read more...

Spring thaw

News
Thursday, April 17, 2014
Spring ThawBY JASON NORRIS | OB BLOGGER

The “polar vortex” of 2014 seems to have finally thawed and we believe this change in weather will bring more sunshine to the U.S. economy as well.


Read more...

Wheel man

March 2014
Tuesday, February 25, 2014
BY LINDA BAKER

Les Schwab has put a premium on customer service since 1952, when legendary namesake Les Schwab founded the company with one store in Prineville. (Schwab died in 2007.) But if the corporate principles remain essentially the same, the world around this iconic Oregon business has changed dramatically.


Read more...
Oregon Business magazinetitle-sponsored-links-02
SPONSORED LINKS