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|Articles - March 2010|
|Sunday, February 14, 2010|
In 2006, Oregon State University professor Jim White was deconstructing Cymbalta, a popular anti-depressant, when he discovered a hole in its molecular skeleton. White saw that as his opening for creating a new, more effective anti-depressant. Low levels of serotonin and norepinephrine — the neurotransmitters in the brain responsible for moods — cause depression. Ideally, anti-depressants stop serotonin and norepinephrine from leaving the brain and entering the blood stream. “To get the best effects, you need to have a balance of these two,” White says. “That hasn’t been achieved with any of the known anti-depressants.” His new compound showed strong interactions with both neurotransmitters when tested artificially and with rats. It could avoid common side effects and work more quickly than current drugs. “Our compound … is closer to the ‘holy grail’ of a perfectly balanced anti-depressant,” White says. He won’t know how effective the drug is until it’s tested on patients, but White and co-inventor and consultant David Wong are seeking a commercial partner to invest and develop the drug. White hopes the drug will be cheaper than other anti-depressants, or even generic versions. That, of course, depends on business, not chemistry.
Monday, January 26, 2015
BY AMY MILSHTEIN | PHOTOS BY JASON E. KAPLAN
The Jade International District, already Portland's center of Asian life, is poised for rejuvenation. Where does that leave the westside's historic Chinatown?
Tuesday, February 24, 2015
BY LINDA BAKER | OB EDITOR
At Oregon State University, a 21st century version of the bad dream — nuclear terrorism — is alive and well. This winter, the Department of Nuclear Physics and Radiation Health Physics created a new interdisciplinary graduate emphasis in nuclear forensics, a Sherlock Holmes-sounding program that aims to identify how and where confiscated nuclear and radiological materials were created.
Friday, January 23, 2015
BY KIM MOORE | OB RESEARCH EDITOR
Carbon pricing is gaining momentum in Oregon, sparking concern for energy-intensive businesses — but also opportunity to expand a homespun green economy.
Friday, March 06, 2015
BY JEFF DELKIN | OP-ED CONTRIBUTOR
As a local business owner, I believe it’s important to build our economy on a platform of conservation values.
Thursday, February 05, 2015
BY JACOB PALMER | OB DIGITAL NEWS EDITOR
We ask chiefs of staff for the scoop on Oregon legislators.
Tuesday, January 27, 2015
Power Lunch at the Imperial.
Friday, February 20, 2015
BY AMY MILSHTEIN | OB CONTRIBUTOR
Don’t just sit there. For a healthy workplace, move up and down — and all around.
|The 100 Best Companies to Work For in Oregon|
|Help Wanted: Poached Jobs aids restaurateurs |
|How Oregon will survive the loss of Hanjin|
|On the Brink|
|Thy neighbor's house|
|How a Utah-based essential oils company cornered the Oregon market|
|640,000 Altimas recalled by Nissan|
|Sellers of the Snuggie nicked $8M for deceptive marketing|
|Obama's veto of Keystone XL pipeline withstands Senate override attempt|
|Production of larger iPad delayed|
|McDonalds pledges to stop selling chicken raised with antibiotics|
|Uber invests in mapping software, setting up contention with Google|
|Bill Gates leads Forbes' richest people list|
Generations of students and graduates have been plagued by the question: What is my true calling in life? Four alumni from Corban University’s Hoff School of Business who graduated in different decades say the school helped them find the answer by giving them a practical, well-rounded education.
It’s happening whether anyone’s ready or not. Businesses here in Oregon and across the U.S. are already experiencing the effects of the largest generational shift in recent history, and these changing tides will impact every level of the workplace — from a company’s executive leadership to its cultural core.
Success stories spotlight meaningful career opportunities in Oregon's diverse and lucrative tourism industry.
QuickBooks Enterprise Users Attend Free
Dream Change, Inc., a nonprofit organization, opens registration for its new groundbreaking event – the Love Summit – on June 13, 2015 at Wieden+Kennedy advertising agency headquarters in Portland.
Parkinson's Resources of Oregon (PRO) is pleased to announce, long standing Intel manager, Kelly Sweeney has joined the agency’s Board of Directors as a member at large.