OSU professor develops a better anti-depressant

| Print |  Email
Articles - March 2010
Sunday, February 14, 2010

nexttest2In 2006, Oregon State University professor Jim White was deconstructing Cymbalta, a popular anti-depressant, when he discovered a hole in its molecular skeleton. White saw that as his opening for creating a new, more effective anti-depressant. Low levels of serotonin and norepinephrine — the neurotransmitters in the brain responsible for moods — cause depression. Ideally, anti-depressants stop serotonin and norepinephrine from leaving the brain and entering the blood stream. “To get the best effects, you need to have a balance of these two,” White says. “That hasn’t been achieved with any of the known anti-depressants.” His new compound showed strong interactions with both neurotransmitters when tested artificially and with rats. It could avoid common side effects and work more quickly than current drugs. “Our compound … is closer to the ‘holy grail’ of a perfectly balanced anti-depressant,” White says. He won’t know how effective the drug is until it’s tested on patients, but White and co-inventor and consultant David Wong are seeking a commercial partner to invest and develop the drug. White hopes the drug will be cheaper than other anti-depressants, or even generic versions. That, of course, depends on business, not chemistry.

AMANDA WALDROUPE
 

Comments   

 
Guest
0 #1 Generic Cymbalta is still a great option but anything that helps is great!Guest 2015-02-20 12:46:53
Especially now that so many generics are coming onto the market, it's great that so many people are finding help with depression and so much research is going into expanding what some of these foundational drugs COULD be. In the mean-time, people can still benefit from traditional generic medications, especially with some sites offering secure and very private ways to purchase them and have them delivered. We have some great information on Cymbalta at our Canadian Pharmacy's website at I believe we're a perfect example of how the patent expiration is starting to be to the advantage of the consumer. We're grateful for the work that Eli Lilly did and now more people can be helped with issues such as the depression that Cymbalta helps to fight. Located in Canada, we have some great information as well as secure resources for people to both securely and privately find generic Cymbalta so that they get all of the benefits at a fraction of the cost. Our company is one of the few Online Canadian Pharmacies legitimate enough to be able to directly accept Visa and Mastercard directly on our site. Visit us online to take advantage of our Cymbalta research and some of the best value online.
http://canadapharmacyrx.com/generic-cymbalta.html in case anyone would like to learn more about its benefits and affects.
Quote | Report to administrator
 

More Articles

Reader Input: Energy Overload

June 2015
Wednesday, July 15, 2015

We asked readers to weigh in on the fossil fuel-green energy equation.


Read more...

The Backstory: Portland Youth Builders

The Latest
Wednesday, June 03, 2015
blog002 1BY JASON E. KAPLAN | STAFF PHOTOGRAPHER

As part of our green workplaces story, Oregon Business checked out a community service project undertaken by Portland Youth Builders, a nonprofit alternative high school. In partnership with Whole Foods, PYB built garden boxes for a Home Forward  housing site. Home Forward is a government agency that provides housing for low income residents and people with disabilities.


Read more...

Brain Storm

July/August 2015
Monday, July 13, 2015
BY CAMILLE GRIGSBY-ROCCA

Can the brave new world of neurotechnology help an OHSU surgeon find a cure for obesity?


Read more...

Department of Self-Promotion

Linda Baker
Wednesday, June 17, 2015

061715-awards1Oregon Business wins journalism awards.


Read more...

Downtime with Debra Ringold

July/August 2015
Monday, July 13, 2015
BY JACOB PALMER

Dean of the Atkinson Graduate School of Management, Willamette University


Read more...

Preserving the Legacy

July/August 2015
Monday, July 13, 2015
BY KIM MOORE | PHOTOS BY JASON E. KAPLAN

A New York floral and gift business takes on the iconic Harry & David brand.


Read more...

5 things to know about veterans in the workforce

The Latest
Wednesday, July 01, 2015
070215-vetsthumbBY JACOB PALMER | DIGITAL NEWS EDITOR

There are more than 10 million former military members working in the United States.


Read more...
Oregon Business magazinetitle-sponsored-links-02
SPONSORED LINKS