Sponsored by Oregon Business

OSU professor develops a better anti-depressant

| Print |  Email
Articles - March 2010
Sunday, February 14, 2010

nexttest2In 2006, Oregon State University professor Jim White was deconstructing Cymbalta, a popular anti-depressant, when he discovered a hole in its molecular skeleton. White saw that as his opening for creating a new, more effective anti-depressant. Low levels of serotonin and norepinephrine — the neurotransmitters in the brain responsible for moods — cause depression. Ideally, anti-depressants stop serotonin and norepinephrine from leaving the brain and entering the blood stream. “To get the best effects, you need to have a balance of these two,” White says. “That hasn’t been achieved with any of the known anti-depressants.” His new compound showed strong interactions with both neurotransmitters when tested artificially and with rats. It could avoid common side effects and work more quickly than current drugs. “Our compound … is closer to the ‘holy grail’ of a perfectly balanced anti-depressant,” White says. He won’t know how effective the drug is until it’s tested on patients, but White and co-inventor and consultant David Wong are seeking a commercial partner to invest and develop the drug. White hopes the drug will be cheaper than other anti-depressants, or even generic versions. That, of course, depends on business, not chemistry.



0 #1 Generic Cymbalta is still a great option but anything that helps is great!Guest 2015-02-20 12:46:53
Especially now that so many generics are coming onto the market, it's great that so many people are finding help with depression and so much research is going into expanding what some of these foundational drugs COULD be. In the mean-time, people can still benefit from traditional generic medications, especially with some sites offering secure and very private ways to purchase them and have them delivered. We have some great information on Cymbalta at our Canadian Pharmacy's website at I believe we're a perfect example of how the patent expiration is starting to be to the advantage of the consumer. We're grateful for the work that Eli Lilly did and now more people can be helped with issues such as the depression that Cymbalta helps to fight. Located in Canada, we have some great information as well as secure resources for people to both securely and privately find generic Cymbalta so that they get all of the benefits at a fraction of the cost. Our company is one of the few Online Canadian Pharmacies legitimate enough to be able to directly accept Visa and Mastercard directly on our site. Visit us online to take advantage of our Cymbalta research and some of the best value online.
http://canadapharmacyrx.com/generic-cymbalta.html in case anyone would like to learn more about its benefits and affects.
Quote | Report to administrator

More Articles

Big Trouble in China?

Guest Blog
Tuesday, August 18, 2015
0818-wellmanthumbBY JASON NORRIS | CFA

Earlier this month, the People’s Bank of China (PBoC) announced they were going to devalue their currency, the Renminbi. While the amount of the targeted change was to be roughly 2 percent, investors read a lot more into the move. The Renminbi had been gradually appreciating against the U.S. dollar (see chart) as to attempt to alleviate concerns of being labeled a currency manipulator.


Up on the Roof

September 2015
Wednesday, August 19, 2015

In 2010 Vanessa Keitges and several investors purchased Portland-based Columbia Green Technologies, a green-roof company. The 13-person firm has a 200% annual growth rate, exports 30% of its product to Canada and received its first infusion of venture capital in 2014 from Yaletown Venture Partners. CEO Keitges, 40, a Southern Oregon native who serves on President Obama’s Export Council, talks about market innovation, scaling small business and why Oregon is falling behind in green-roof construction. 


Back to School

September 2015
Wednesday, August 19, 2015

Oregon is home to an abundance of gritty warehouses reborn as trendy office spaces, as well as crafty hipsters turned entrepreneurs. Does the combination yield an equally bounteous office products sector? Not so much. Occupying the limited desk jockey space are Field Notes, a spinoff of Portland’s Draplin Design Company, and Schuttenworks, known for whittling Apple device stands. For a full complement of keyboard trays, docking stations and mouse pads, check out the GroveMade line, guaranteed to boost the cachet of even the lowliest cubicle drone. 


Counterpoint: CLT not as green as people think

Contributed Blogs
Wednesday, September 16, 2015
photo-flickr-glasseyes viewthymbBY GREGG LEWIS | OP-ED

The issue of green-washing remains a significant challenge to those of us who would like to see the building sector in this country do more than make unverifiable claims of sustainability. Transparency about the impacts of a given material is the only way to allow designers to make intelligent choices when selecting building products.


Big Geek

October 2015
Monday, September 28, 2015

To attract technology companies, the U.S. Bancorp Tower repositions itself as open, light and playful.


Aim High

September 2015
Thursday, August 20, 2015

We get the education we deserve.


Salad Days

October 2015
Monday, September 28, 2015

How Portland's Garden Bar plans to become the Starbucks of salad.

Oregon Business magazinetitle-sponsored-links-02