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|Articles - March 2010|
|Sunday, February 14, 2010|
In 2006, Oregon State University professor Jim White was deconstructing Cymbalta, a popular anti-depressant, when he discovered a hole in its molecular skeleton. White saw that as his opening for creating a new, more effective anti-depressant. Low levels of serotonin and norepinephrine — the neurotransmitters in the brain responsible for moods — cause depression. Ideally, anti-depressants stop serotonin and norepinephrine from leaving the brain and entering the blood stream. “To get the best effects, you need to have a balance of these two,” White says. “That hasn’t been achieved with any of the known anti-depressants.” His new compound showed strong interactions with both neurotransmitters when tested artificially and with rats. It could avoid common side effects and work more quickly than current drugs. “Our compound … is closer to the ‘holy grail’ of a perfectly balanced anti-depressant,” White says. He won’t know how effective the drug is until it’s tested on patients, but White and co-inventor and consultant David Wong are seeking a commercial partner to invest and develop the drug. White hopes the drug will be cheaper than other anti-depressants, or even generic versions. That, of course, depends on business, not chemistry.
Wednesday, May 28, 2014
More than 350 people turned out today for Oregon Business magazine’s sixth annual celebration of the 100 Best Green Companies to Work For in Oregon.
Thursday, June 05, 2014
BY HANNAH WALLACE | OB BLOGGER
What does it take to launch and run one of these mobile food businesses?
Tuesday, May 27, 2014
Oregon is known for its green-minded citizens, and many workers are attracted to firms and organizations that practice green, not just pay lip service to it.
Wednesday, July 02, 2014
BY JESSICA RIDGWAY | OB WEB EDITOR
Dress for Success Oregon promotes the economic independence of disadvantaged women by providing professional attire, a network of support and career development tools.
Thursday, May 29, 2014
BY SOPHIA BENNETT
Tillamook expands its tourism niche.
Thursday, July 03, 2014
BY TED AUSTIN & MIKE BAELE | GUEST CONTRIBUTORS
The Office of Economic Analysis announced that Oregon is currently enjoying the strongest job growth since 2006. While this resurgence has been welcome, the lingering effects of the 2008 “Great Recession” continues to affect Oregon businesses, especially with regard to estate planning and business succession.
Thursday, May 29, 2014
BY JESSICA RIDGWAY
Brad Baker, CEO and co-founder of Works Electric, is a good husband. His wife, an OHSU employee, sought a more efficient way to commute up Marquam “Pill” Hill, so she asked Baker to build a transportation solution.
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Vigilant enters a New Year with a new president.
How George Fox has become one of Oregon's largest private universities.
Forest Grove sees growth in the burgeoning food and beverage scene.
Geffen Mesher is saddened to announce the passing of long-time shareholder, Tom “Mike” Anderson, who died on July 10, 2014, from liver disease diagnosed after recent heart surgery. He was 55 years old.
Fifteen Lane Powell attorneys have been named 2014 “Oregon Super Lawyers,” and another five attorneys have been named as “Oregon Rising Stars” by Super Lawyers magazine.
From its first-ever member forum, to upcoming Board elections, the Oregon-based, non-profit health organization is focused on letting members control their healthcare destiny.