Home Back Issues March 2010 OSU professor develops a better anti-depressant

OSU professor develops a better anti-depressant

| Print |  Email
Articles - March 2010
Sunday, February 14, 2010

nexttest2In 2006, Oregon State University professor Jim White was deconstructing Cymbalta, a popular anti-depressant, when he discovered a hole in its molecular skeleton. White saw that as his opening for creating a new, more effective anti-depressant. Low levels of serotonin and norepinephrine — the neurotransmitters in the brain responsible for moods — cause depression. Ideally, anti-depressants stop serotonin and norepinephrine from leaving the brain and entering the blood stream. “To get the best effects, you need to have a balance of these two,” White says. “That hasn’t been achieved with any of the known anti-depressants.” His new compound showed strong interactions with both neurotransmitters when tested artificially and with rats. It could avoid common side effects and work more quickly than current drugs. “Our compound … is closer to the ‘holy grail’ of a perfectly balanced anti-depressant,” White says. He won’t know how effective the drug is until it’s tested on patients, but White and co-inventor and consultant David Wong are seeking a commercial partner to invest and develop the drug. White hopes the drug will be cheaper than other anti-depressants, or even generic versions. That, of course, depends on business, not chemistry.

AMANDA WALDROUPE
 

More Articles

The 2014 List: The Top 33 Small Companies to Work, For in Oregon

March 2014
Thursday, February 27, 2014

100best14logoWebOur 100 Best Companies project turned 21 this year, so pop open the Champagne. Our latest survey gives us plenty to cheer.

 


Read more...

Tech makes the world go round

Contributed Blogs
Thursday, March 20, 2014
03.20.14 thumb internetBY JASON NORRIS | GUEST BLOGGER

I don’t think anyone can (or should) remember what it was like to get things done without the internet. This milestone in technology has certainly benefited brick-and-mortar companies and subsequently launched a new era of businesses.


Read more...

Branching out

March 2014
Tuesday, February 25, 2014
DSC04185BY LINDA BAKER

A blueberry bush is a blueberry bush — except when it’s a blueberry tree.


Read more...

How to boost web traffic

News
Thursday, April 10, 2014
BY JESSICA RIDGWAY  | OB WEB EDITOR

04.10.14 thumb seo-trafficSEMpdx hosted a workshop this week for entrepreneurs, website developers and others interested in search engine optimization (SEO).  Here are a few tips and tricks aimed at bumping up your search engine rankings.


Read more...

Revolution in print, pixels and passion

News
Tuesday, March 11, 2014
RyanFrankNewsBY MARK BLAINE | OB BLOGGER

The publisher of the Emerald Media Group moves on, leaving a cutting edge media group that depends on business acumen for its survival.


Read more...

Rapid ascent

March 2014
Tuesday, February 25, 2014
IMG 4255-2BY AMY MILSHTEIN

Kelly Dachtler, president of The Clymb, redefines outdoor retail.


Read more...

The 2014 List: The Top 34 Medium Companies to Work, For in Oregon

March 2014
Thursday, February 27, 2014

100best14logoWebOur 100 Best Companies project turned 21 this year, so pop open the Champagne. Our latest survey gives us plenty to cheer.

 


Read more...
Oregon Business magazinetitle-sponsored-links-02
SPONSORED LINKS