|| Print ||
|Articles - March 2010|
|Sunday, February 14, 2010|
In 2006, Oregon State University professor Jim White was deconstructing Cymbalta, a popular anti-depressant, when he discovered a hole in its molecular skeleton. White saw that as his opening for creating a new, more effective anti-depressant. Low levels of serotonin and norepinephrine — the neurotransmitters in the brain responsible for moods — cause depression. Ideally, anti-depressants stop serotonin and norepinephrine from leaving the brain and entering the blood stream. “To get the best effects, you need to have a balance of these two,” White says. “That hasn’t been achieved with any of the known anti-depressants.” His new compound showed strong interactions with both neurotransmitters when tested artificially and with rats. It could avoid common side effects and work more quickly than current drugs. “Our compound … is closer to the ‘holy grail’ of a perfectly balanced anti-depressant,” White says. He won’t know how effective the drug is until it’s tested on patients, but White and co-inventor and consultant David Wong are seeking a commercial partner to invest and develop the drug. White hopes the drug will be cheaper than other anti-depressants, or even generic versions. That, of course, depends on business, not chemistry.
Wednesday, April 01, 2015
BY LINDA BAKER
Leaders in Oregon's ag sector gathered this morning in Portland’s Coopers Hall winery/taproom to discuss the role of the region as an export gateway, impediments to exporting products and solutions to containerized shipping challenges.
Thursday, March 19, 2015
BY JACOB PALMER | DIGITAL NEWS EDITOR
There are 278 companies licensed to operate as brewery, according to the Oregon Liquor Control Commission. Here are three new beer-making hubs slated to open soon.
Monday, April 27, 2015
BY JACOB PALMER
Live, Work, Play with Christine Jump.
Friday, March 27, 2015
BY AMY MILSHTEIN
Damian Smith bets on changing himself — and Portland — through consulting.
Thursday, April 30, 2015
BY LINDA BAKER | EDITOR
Earlier this week we posted an article from our May issue: It’s a Man's Man’s Man’s World. The story covered the gender divide in tech from the perspective of male workers. Twitter didn’t like it.
Friday, April 17, 2015
PHOTOS BY JASON E. KAPLAN
The 32nd annual CBC attracted a record number of attendees (11,000) to the Oregon Convention Center.
Thursday, April 02, 2015
BY JACOB PALMER | DIGITAL NEWS EDITOR
Are mornings the most productive part of the day? We ask five successful executives how they get off to a good start.
|The Good Hacker|
|Downtime with the director of Barley's Angels|
|It's a Man's Man's Man's World|
|Fighting Fire With Fire|
|Shades of Gray|
|Man for All Seasons|
|Airline earnings are in the bag|
|Trade deficit reaches six-year high|
|Comcast reaching tipping point in Internet subscribers |
|SurveyMonkey CEO dies|
|Labor groups hope franchisees will join fight against fast-food companies|
|Special fee to ship oil proposed|
|Jeff Bezos launches spaceship|
New conference aims to solve challenges, quell fears amid regulatory changes.
Tourism marketing supports entrepreneurship by attracting visitors to all corners of the state.
Beaverton firm's business intelligence platform rivals that of industry heavyweights.
Earlier this month CEO of Gravity Payments, Dan Price, disrupted the payment inequality discussion worldwide by compassionately raising the minimum salary for each one of his 120 employees to $70k and cutting his $1M salary down to $70k.
Thinking about an MBA? Join us for our upcoming Wine & Cheese Information Session to learn more about Concordia University's MBA program.
Providing attendees with unique taste of the Northwest Reception.