OSU professor develops a better anti-depressant

| Print |  Email
Articles - March 2010
Sunday, February 14, 2010

nexttest2In 2006, Oregon State University professor Jim White was deconstructing Cymbalta, a popular anti-depressant, when he discovered a hole in its molecular skeleton. White saw that as his opening for creating a new, more effective anti-depressant. Low levels of serotonin and norepinephrine — the neurotransmitters in the brain responsible for moods — cause depression. Ideally, anti-depressants stop serotonin and norepinephrine from leaving the brain and entering the blood stream. “To get the best effects, you need to have a balance of these two,” White says. “That hasn’t been achieved with any of the known anti-depressants.” His new compound showed strong interactions with both neurotransmitters when tested artificially and with rats. It could avoid common side effects and work more quickly than current drugs. “Our compound … is closer to the ‘holy grail’ of a perfectly balanced anti-depressant,” White says. He won’t know how effective the drug is until it’s tested on patients, but White and co-inventor and consultant David Wong are seeking a commercial partner to invest and develop the drug. White hopes the drug will be cheaper than other anti-depressants, or even generic versions. That, of course, depends on business, not chemistry.

AMANDA WALDROUPE
 

Comments   

 
Guest
0 #1 Generic Cymbalta is still a great option but anything that helps is great!Guest 2015-02-20 12:46:53
Especially now that so many generics are coming onto the market, it's great that so many people are finding help with depression and so much research is going into expanding what some of these foundational drugs COULD be. In the mean-time, people can still benefit from traditional generic medications, especially with some sites offering secure and very private ways to purchase them and have them delivered. We have some great information on Cymbalta at our Canadian Pharmacy's website at I believe we're a perfect example of how the patent expiration is starting to be to the advantage of the consumer. We're grateful for the work that Eli Lilly did and now more people can be helped with issues such as the depression that Cymbalta helps to fight. Located in Canada, we have some great information as well as secure resources for people to both securely and privately find generic Cymbalta so that they get all of the benefits at a fraction of the cost. Our company is one of the few Online Canadian Pharmacies legitimate enough to be able to directly accept Visa and Mastercard directly on our site. Visit us online to take advantage of our Cymbalta research and some of the best value online.
http://canadapharmacyrx.com/generic-cymbalta.html in case anyone would like to learn more about its benefits and affects.
Quote | Report to administrator
 

More Articles

Wildcards

Guest Blog
Tuesday, July 28, 2015
China A SharesBY JASON NORRIS, CFA | OB GUEST BLOGGER

Uncertainty in Greece and China, along with potential interest rate hikes mean investors are looking at the market and nervously questioning where they should be invested.


Read more...

Store Bought

July/August 2015
Friday, July 10, 2015
BY LINDA BAKER

Market of Choice is on a tear. In 2012 the 35-year-old Eugene-based grocery chain opened a central kitchen/distribution center in its hometown. The market opened its third Portland store in the Cedar Mill neighborhood this year; another outpost in Bend broke ground in March. A fourth Portland location is slated for the inner southeast “LOCA” development, a mixed-use project featuring condos and retail. Revenues in 2014 were $175 million, a double-digit increase over 2013. CEO Rick Wright discusses growth, market trends and how he keeps new “foodie” grocery clerks happy.


Read more...

The Private 150: From Strength to Strength

July/August 2015
Monday, July 13, 2015
BY KIM MOORE

Revenues in Oregon's private, for profit sector maintained solid growth as the economy continued to rebound.


Read more...

Best Foot Forward

July/August 2015
Monday, July 13, 2015
BY CHRIS NOBLE

Whether you're stepping out to work or onto the track, Pacific Northwest shoe companies have you covered.


Read more...

Preserving the Legacy

July/August 2015
Monday, July 13, 2015
BY KIM MOORE | PHOTOS BY JASON E. KAPLAN

A New York floral and gift business takes on the iconic Harry & David brand.


Read more...

Fueling Up for the Climb

July/August 2015
Friday, July 10, 2015
BY GREGG MORRIS

Rita Hansen aims to scale natural gas vehicle innovation.


Read more...

Storyteller in Chief: Natural Prophets

July/August 2015
Monday, July 13, 2015
BY SAM BLACKMAN

Storyteller-in-chief with the CEO and co-founder of Elemental Technologies.


Read more...
Oregon Business magazinetitle-sponsored-links-02
SPONSORED LINKS