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|Archives - May 2009|
|Friday, May 01, 2009|
From stronger teeth to sharper eyes to a rewired brain, Oregon innovators are finding ways to keep us living longer and better.
BY JON BELL
Who: Greta Binford, assistant professor of biology
Who: SAM Medical Products
Who: Chrissa Kioussi, assistant professor of pharmacology
Who: Bend Research
What: Drug delivery technology
You can cross your heart and hope to die, but thanks to scientists at Bend Research, you may never have to stick a needle in your eye — at least not to deliver drugs for glaucoma.
“As you can imagine, that’s not a lot of fun,” says Rod Ray, chief executive officer of the 34-year-old Bend medical company.
Among its other innovations, Bend Research is developing new technologies for administering drugs to the eyes, including drops that contain powerful medicine in nanoparticle form. Ray says researchers there have also been working on ways to make drugs more soluble and to target them to specific sites in the body. The latter would not only reduce the amount of drug needed, but would also help ensure that, say, cancer drugs would head straight for a tumor.
“That technology is a really important one for fighting cancer,” says Ray.
Bend Research, which developed the popular one-dose antibiotic Zmax, recently left a 14-year exclusive partnership with the pharmaceutical giant Pfizer, and is currently harvesting new relationships with biotech and drug companies around the world.
Ray says he sees the company continuing to make advances in the pharmaceutical realm and dabbling in the world of diagnostics. A possible next step: a new and better cholesterol test.
Who: Scott Frey, psychology professor
What: Brain adaptation research
Where: University of Oregon, Eugene
If Scott Frey is right about the human brain, we may be in for some monumental shifts in the treatment of everything from strokes to spinal cord damage.
Studying a handful of amputees who’ve been “cured” via hand transplants, Frey has learned that the brain is a mighty organizer. Not only does it reorganize itself after the limb is lost, but it then “re-reorganizes” itself when a new limb is attached. Feeling comes back and the brain begins processing signals from the new hand in the same region it did for the original hand.
“Our case presents the most compelling case that the brain can go back to the way it was,” Frey says.
The broader implication could theoretically mean that the brain would be able to rewire itself in, say, a paralyzed patient whose damaged spinal cord has been repaired by stem cells. Damage from strokes, concussive head injuries and diseases such as multiple sclerosis might also someday be abated with a better understanding of how the brain adapts.
Frey’s next wave of related research, funded by the Department of Defense, finds him recruiting arm and hand amputees to learn more about the brain’s role in phantom pain and the nearly 50% of upper limb amputees who reject prostheses.
“I would like to see us get a better understanding of these basic brain changes,” he says, “and the extent to which they can be reversed.”
Who: Neda Shamie, MD
What: Cataract and corneal surgery
Where: Legacy’s Devers Eye Institute, Portland
Oregon’s the right location for snowy mountains, microbrews and, apparently, afflictions of the eye.
“Oregon is a great place to be if you have an eye disease,” says Neda Shamie, a corneal and laser refractive surgeon at Legacy Good Samaritan Hospital’s Devers Eye Institute.
Shamie is one of Devers’ surgeons who specializes in some of the latest and greatest procedures out there. One example: advanced intraocular lens surgery for cataracts, where surgeons implant premium lenses that restore vision to near 20-20 and usually render reading glasses unnecessary.
But where Shamie and Devers really shine is in the realm of the cornea. Her colleague, Mark Terry, revolutionized cornea transplants 10 years ago with a technique that replaces only the damaged layer of the cornea, not the entire thickness as had been standard practice. Shamie herself has done more than 100 of those surgeries since joining Devers in 2006.
The institute is also one of the only facilities in Oregon to offer artificial cornea implanting, a new option for high-risk patients who’ve had multiple regular implants fail.
“There are books that can be written on what’s to come,” says Shamie.
Wednesday, June 10, 2015
Jeff Lang and his wife Rae used to dole out campaign checks like candy. “We were like alcoholics,” Lang says. ”We couldn’t just give a little.”
Thursday, June 25, 2015
An international architecture firm known for its design of the National September 11 Memorial Museum Pavilion in New York unveiled its plan this week for a modern indoor/outdoor food market at the foot of the Morrison Bridge in downtown Portland.
Tuesday, July 14, 2015
The Big One serves as an allegory for Portland, a city that earns plaudits for lifestyle and amenities but whose infrastructure is, literally, crumbling.
Thursday, June 11, 2015
In 2014, total revenue for camping and day use in Oregon State Parks was a little more than $17 million. That figure may even higher this year "because we've had exceptionally nice weather," Hughes says.
Thursday, July 09, 2015
The sweltering weather didn't keep the crowds away. Although the numbers were down slightly from last year, the Oregon Food Bank raised $850,636 to fight hunger. About 80,000 people attended despite temperatures in the upper 90s.
Monday, July 13, 2015
BY CHRIS NOBLE
Whether you're stepping out to work or onto the track, Pacific Northwest shoe companies have you covered.
Friday, July 17, 2015
Photographer Jason Kaplan takes a look at Murray's Pharmacy in Heppner. The family owned business is run by John and Ann Murray, who were featured in our July/August cover story: 10 Innovators in Rural Health Care.
|10 Innovators in Rural Health|
|The Private 150: From Strength to Strength|
|Downtime with Debra Ringold|
|Farm in a Box|
|Flattery with Numbers|
|Preserving the Legacy|
|Fiat Chrysler must offer to buy back 500K Dodge Ram trucks|
|Portland kayakers protest ship owned by Shell Oil Company|
|Amazon earns $92M in profit|
|Under Armour bests Q2 earnings expectations|
|More than a hundred passengers forced to stay overnight at PDX|
|Immunization rates to be available to parents|
|CEO who pledged $70K minimum wage sued by brother|
Court experience helps legal firm anticipate potential problems for clients and prevent expensive litigation.
When Garmin AT needed to consolidate operations for its 550 employees, it scanned its entire corporate map for possible sites.
The technology industry is always in flux. And this rapid rate of change poses challenges to companies ranging from nimble startups aiming to make their mark to established organizations fighting to remain relevant. This is particularly true in the competitive digital display market, where an Oregon company has been at the forefront of nearly every major breakthrough in the last three decades.
A look back at the shifting sands of Portland’s growth and development.
Robert S. Wiggins has joined Lane Powell as a Shareholder in the Corporate/M&A Practice Group. Wiggins is a well-known lawyer, entrepreneur, and investor with more than 30 years of experience leading and advising established and emerging companies in the Pacific Northwest. Wiggins will focus his practice on offering outside general counsel services, including general corporate and board representation, business transactions and capital events.
DEDICATION PARTY: Help the Port of The Dalles celebrate its newest shovel-ready industrial land Friday, July 31, from 1:30 to 4 p.m.