Cell power

| Print |  Email
Articles - May 2014
Monday, April 28, 2014

next-mitoqBY LINDA BAKER

Found in all cells, mitochondria are tube shape “organelles” that convert food into useful energy; when mitochondria fail, disease results. Now researchers at OHSU have found that an antioxidant targeting “mitochondrial dysfunction” can help alleviate symptoms in mice that have a multiple sclerosis-type disease. MS is a condition in which the body’s immune system attacks the myelin, a protective sheath surrounding nerve fibers of the central nervous system. Symptoms can include blurred vision, numbness and paralysis. Treated with the antioxidant — called MitoQ — afflicted mice showed reduced demyelination and inflammation of the neurons, says P. Hemachandra Reddy, an associate scientist in the Division of Neuroscience at OHSU’s Oregon National Primate Research Center. The antioxidant appears to work by entering neuronal cells quickly, then “scavenging” the free radicals that can damage cells — damage linked to numerous maladies. The next step is to understand exactly how MitoQ protects mitochondria within the brains of mice with the MS-type condition — and then conduct trials on humans. Although MitoQ was designed more than a dozen years ago, this is the first time it has been tested as an MS therapy. “This is a major breakthrough for MS patients,” says Reddy.

 

 

More Articles

Oregon businesses face destruction from future earthquake

The Latest
Wednesday, May 20, 2015
htctthumb1BY KIM MOORE | RESEARCH EDITOR

An earthquake would completely destroy many Oregon businesses, highlighting the urgent need for the private and public sectors to collaborate on shoring up disaster preparedness, said panelists at an Oregon Business breakfast summit today.


Read more...

Knight Cancer Challenge No Biotech Dream

May 2015
Monday, April 27, 2015
BY JOE CORTRIGHT

The Knight challenge is an important instance of philanthropy. But we should not assume it will magically transform OHSU into a business- and job-spinning engine for the local economy.


Read more...

100 Best Green Workplaces announced

News
Wednesday, May 27, 2015
OBM-100-best-Green-logo-2015-1000pxwBY LINDA BAKER | EDITOR

More than 250 people turned out today for Oregon Business magazine’s seventh annual celebration of the 100 Best Green Companies to Work For in Oregon.


Read more...

Picture This

May 2015
Monday, April 27, 2015
BY JACOB PALMER

As a general rule, the more people with autism can be provided with visual cues, the better they will be able to understand and manage their environment. It’s a lesson Tom Keating learned well. The 61-year-old Eugene grant writer spent 31 years taking care of his autistic brother James, and in the late 1980s developed a spreadsheet that created a series of nonsense characters that grew or shrank depending on how much money James had in his account. 


Read more...

Short Shrift:The threat of just-in-time scheduling

May 2015
Monday, April 27, 2015
BY AMY MILSHTEIN

Companies can benefit when they use software to meet staffing requirements and address employees' family and life commitments.


Read more...

An uncertain future

Guest Blog
Thursday, May 21, 2015
norristhumbBY JASON NORRIS | GUEST BLOGGER

Uncertainty is a part of doing business, whether in through the lens of investment opportunities and risks or the business of running an enterprise.


Read more...

Nine lives

Linda Baker
Friday, May 22, 2015
0f4f7bfBY LINDA BAKER | EDITOR

Roy Kaufmann always lands on his feet.


Read more...
Oregon Business magazinetitle-sponsored-links-02
SPONSORED LINKS