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|Articles - February 2014|
|Tuesday, January 21, 2014|
BY LINDA BAKER
Although millions of people take anti-depressants, scientists know astonishingly little about how these therapies actually work. “It was kind of hit or miss; the measure was whether the person got better or not,” says Eric Gouaux, a senior scientist at OHSU’s Vollum Institute. Now Gouaux and his lab are shedding new light on a previously cloudy process: Their research focuses on the dopamine transporter, a protein that helps regulate levels of dopamine, a neurotransmitter. Abnormal levels of dopamine are present in a variety of disorders, including depression. So what is Gouaux’s scientific breakthrough? “For the first time, we are able to visualize the molecular details of what the antidepressant does when it binds to a biologically active site,” he says. In layman’s terms: “We can finally see the lock in which keys have been placed.” The key to success was solving the 3-D crystal structure of the dopamine transporter, a notoriously difficult task that has stymied scientists for decades. The next step is to gain insight into better therapies, as well as to visualize the impact of drugs such as methamphetamine and cocaine, which exert much of their biological effect by inhibiting the dopamine transporter. In the meantime, Gouaux, who has labored four years on the project, is pretty happy with his lab’s pioneering discovery. “It’s been a pilgrimage,” he says.
Wednesday, August 27, 2014
Kim Ierian, President of Concorde Career Colleges, and Deborah Edward, Executive Director of Business for Culture & the Arts, share their recent reads.
Friday, August 15, 2014
In this week's poll, we asked readers: "Who should pay for the troubled Cover Oregon website?" Here are the results.
Tuesday, August 26, 2014
BY JESSICA RIDGWAY
September's Launch article features Orchid Health, BuddyUp and Inter-Europe Consulting.
Wednesday, August 27, 2014
BY LEE VAN DER VOO
By now we’ve all read the headlines: Starbucks is giving away free degrees. Except it isn’t.
Thursday, July 24, 2014
BY LINDA BAKER | OB EDITOR
Remember the naysayers? Those who called the South Waterfront aerial tram a boondoggle? Those who rejoiced at the massive sell off of luxury condos at the John Ross and Atwater Place?
Wednesday, August 20, 2014
By Kim Moore | OB Editor
The 2015 survey launched this week. It is open to for-profit private and public companies that have at least 15 full- or part-time employees in Oregon.
Wednesday, August 13, 2014
BY TOM COX | OB BLOGGER
When I say, “Your Employee is Always Right,” I do not mean “right about the facts,” but rather “right about how they feel” and “right about how they want to be led.”
|A Taste of Heaven|
|A Good Leap Forward|
|Fast Food Slows Down|
|Startup or Grow Up?|
|Tight and Loose|
|United Airlines offers $100K buyouts to flight attendants|
|Microsoft acquires popular game 'Minecraft'|
|Cognizant to buy TriZetto|
|Apple hits new record with iPhone 6 preorders|
|U.S. retail sales driven by car, health purchases|
|New iPhones face shipping delays|
|New York, nation pause to remember 9/11|
Is your business ready to join us in the call for action? This opening panel includes Oregon businesses who will discuss why they signed the Oregon Climate Declaration, the investments they are making to reduce carbon emissions, and how their actions are affecting their companies.
Get ready for two days of special events produced with the EPA, Portland Timbers and ISOS before and after the GoGreen Conference on October 16.
First Call Resolution targets employee well-being and client satisfaction.
How six leading foundations are working together for a better Oregon.
Vigilant enters a New Year with a new president.
Sussman Shank is proud to announce that eight attorneys have been selected by their peers for inclusion in the 2015 edition of Best Lawyers in America, the oldest and most respected peer-review publication in the legal profession.
Lane Powell Shareholder William T. Patton has been appointed to the board of directors for Cascade AIDS Project, an organization that provides educational services and outreach to thousands of Oregonians living with HIV/AIDS.