|| Print ||
|Articles - February 2014|
|Tuesday, January 21, 2014|
BY LINDA BAKER
Although millions of people take anti-depressants, scientists know astonishingly little about how these therapies actually work. “It was kind of hit or miss; the measure was whether the person got better or not,” says Eric Gouaux, a senior scientist at OHSU’s Vollum Institute. Now Gouaux and his lab are shedding new light on a previously cloudy process: Their research focuses on the dopamine transporter, a protein that helps regulate levels of dopamine, a neurotransmitter. Abnormal levels of dopamine are present in a variety of disorders, including depression. So what is Gouaux’s scientific breakthrough? “For the first time, we are able to visualize the molecular details of what the antidepressant does when it binds to a biologically active site,” he says. In layman’s terms: “We can finally see the lock in which keys have been placed.” The key to success was solving the 3-D crystal structure of the dopamine transporter, a notoriously difficult task that has stymied scientists for decades. The next step is to gain insight into better therapies, as well as to visualize the impact of drugs such as methamphetamine and cocaine, which exert much of their biological effect by inhibiting the dopamine transporter. In the meantime, Gouaux, who has labored four years on the project, is pretty happy with his lab’s pioneering discovery. “It’s been a pilgrimage,” he says.
Wednesday, February 25, 2015
BY JASON NORRIS, CFA | OB GUEST BLOGGER
Pets.com, GeoCities, eToys, and WorldCom … blasts-from-the-past that all signify the late 1990s Internet bubble. Yet we believe the dynamics of the market, specifically in technology stocks, are much different today than it was during the late 1990s.
Monday, February 23, 2015
Yeah, we know: Oregonians are way too cool for umbrellas. But today’s stylish, high-tech models will soften the resistance of the most rain hardened.
Friday, February 20, 2015
BY LINDA BAKER | OB EDITOR
Vacasa may lack the name recognition of Airbnb. But not for long.
Thursday, March 19, 2015
BY DAN COOK | Photos by Jason E. Kaplan
An alliance of developers, academics and timber industry executives wants to position Oregon as a front runner in the glamorous new world of wooden skyscrapers.
Friday, March 27, 2015
BY OB STAFF
New events series brings magazine to life.
Friday, March 27, 2015
BY JACOB PALMER
Five years in the making, the Portland Mercado — the city’s first Latino public market — will celebrate its grand opening April 11. A $3.5 million public-private partnership spearheaded by Hacienda CDC, the market will house 15 to 20 businesses in the food, retail and service sectors. It has some big-name funders, including the Paul G. Allen Family Foundation and JPMorgan Chase. The project goals are equally ambitious: to improve cross-cultural understanding, alleviate poverty and spur community economic development.
Friday, February 20, 2015
BY AMY MILSHTEIN | OB CONTRIBUTOR
Multilevel marketing, health claims and zyto scanner biofeedback machines: How dōTERRA thrives in Oregon.
|Get on the bus!|
|Bike Chic: 7 stylish options for cyclists|
|Beam Me Up|
|Emperor of the Sea|
|Epitaph for a Boondoggle|
|Student loan debtors face default in repayment strike|
|Jay Z unveils streaming music service|
|Volvo plans $500M car factory in US|
|Oil crash starting to hurt in Texas|
|Swiss bankers guilty of tax fraud avoid jail|
|US grants Texan rhino hunter permit to bring back trophy|
|Norwegian Air tweaks cockpit rules after Germanwings crash|
A new report highlights how Oregon bankers are giving back to their communities.
Since 1932 Tidewater Transportation & Terminals (operating as Tidewater Barge Lines and Tidewater Terminal Company) has operated a multicommodity transportation and terminal company based in Vancouver, Washington. The friendly expression on the company’s shipping containers reflects the attitude of about 330 safety and community-conscious employees but belies how complicated the barge business really is.
The Port of The Dalles has run marine facilities since the 1930s, but they are part of a larger mission to strengthen the local economy. They focus on regional economic development with a strong bent toward adding good-paying jobs in high tech, manufacturing and other industries.
The Atkinson Graduate School of Management at Willamette University has maintained its business accreditation by AACSB International—The Association to Advance Collegiate Schools of Business.
Like the advent of the locomotive, the cloud creates business opportunities that simply weren’t possible before now. Get up to speed fast in May at an exciting cloud-empowered Portland event.
Registration is now open for Portland Business Alliance’s Annual Meeting, one of the largest business gatherings in Portland each year.