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|Articles - March 2013|
|Monday, February 25, 2013|
BY LINDA BAKER
Itchy and inflamed skin is the bane of existence for people who suffer from atopic dermatitis, a type of eczema most common in infancy that also affects millions of adults around the world. Now scientists at Oregon State University have discovered an underlying genetic cause for the condition, a discovery that may lead to more effective therapies. The culprit is “Ctip2,” a protein and “master” regulator that controls the production of lipids, the fats that help keep the skin healthy. The regulator also suppresses a protein manufactured by skin cells that can cause irritation. In animal studies, researchers found that malfunctioning Ctip2 can produce eczema either by reducing the lipids in the skin or by allowing the protein that triggers inflammation to form. To alleviate both problems, scientists are working on topical compounds that would restore fat levels and possibly increase the expression of Ctip2, said Arup Indra, an associate professor in the OSU College of Pharmacy. The development of such treatments could eventually lead to personalized gene therapies, says Indra. “Our understanding of genomics is improving day by day, even hourly,” Indra says. “The challenge is using that understanding to develop therapies that are effective.”
Wednesday, June 10, 2015
Jeff Lang and his wife Rae used to dole out campaign checks like candy. “We were like alcoholics,” Lang says. ”We couldn’t just give a little.”
Monday, July 13, 2015
BY JACOB PALMER
Holding a Power Lunch at Veritable Quandary in downtown Portland.
Monday, July 13, 2015
BY KIM MOORE | PHOTOS BY JASON E. KAPLAN
A New York floral and gift business takes on the iconic Harry & David brand.
Wednesday, July 15, 2015
We asked readers how Obamacare has impacted their business.
Thursday, June 11, 2015
In 2014, total revenue for camping and day use in Oregon State Parks was a little more than $17 million. That figure may even higher this year "because we've had exceptionally nice weather," Hughes says.
Wednesday, June 17, 2015
Friday, July 10, 2015
BY JACOB PALMER
Most of the food Americans consume is trucked in from hundreds of miles away. Eric Wilson, co-founder and CEO of Gro-volution, wants to change that. So this past spring, the Air Force veteran and former greenhouse manager started work on an alternative farming system he claims is more efficient than conventional agriculture, and also shortens the distance between the consumer and the farm.
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|Preserving the Legacy|
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|Downtime with Debra Ringold|
|Amazon earns $92M in profit|
|Under Armour bests Q2 earnings expectations|
|More than a hundred passengers forced to stay overnight at PDX|
|Immunization rates to be available to parents|
|CEO who pledged $70K minimum wage sued by brother|
|Toshiba executives resign over $1.2B accounting fraud|
|Elusive snow leopard captured in photos|
Court experience helps legal firm anticipate potential problems for clients and prevent expensive litigation.
When Garmin AT needed to consolidate operations for its 550 employees, it scanned its entire corporate map for possible sites.
The technology industry is always in flux. And this rapid rate of change poses challenges to companies ranging from nimble startups aiming to make their mark to established organizations fighting to remain relevant. This is particularly true in the competitive digital display market, where an Oregon company has been at the forefront of nearly every major breakthrough in the last three decades.
A look back at the shifting sands of Portland’s growth and development.
Robert S. Wiggins has joined Lane Powell as a Shareholder in the Corporate/M&A Practice Group. Wiggins is a well-known lawyer, entrepreneur, and investor with more than 30 years of experience leading and advising established and emerging companies in the Pacific Northwest. Wiggins will focus his practice on offering outside general counsel services, including general corporate and board representation, business transactions and capital events.
DEDICATION PARTY: Help the Port of The Dalles celebrate its newest shovel-ready industrial land Friday, July 31, from 1:30 to 4 p.m.