Home Back Issues March 2013 Next: ditch the itch

Next: ditch the itch

| Print |  Email
Articles - March 2013
Monday, February 25, 2013

 

BY LINDA BAKER

0313 NextItchy and inflamed skin is the bane of existence for people who suffer from atopic dermatitis, a type of eczema most common in infancy that also affects millions of adults around the world. Now scientists at Oregon State University have discovered an underlying genetic cause for the condition, a discovery that may lead to more effective therapies. The culprit is “Ctip2,” a protein and “master” regulator that controls the production of lipids, the fats that help keep the skin healthy. The regulator also suppresses a protein manufactured by skin cells that can cause irritation. In animal studies, researchers found that malfunctioning Ctip2 can produce eczema either by reducing the lipids in the skin or by allowing the protein that triggers inflammation to form. To alleviate both problems, scientists are working on topical compounds that would restore fat levels and possibly increase the expression of Ctip2, said Arup Indra, an associate professor in the OSU College of Pharmacy. The development of such treatments could eventually lead to personalized gene therapies, says Indra. “Our understanding of genomics is improving day by day, even hourly,” Indra says. “The challenge is using that understanding to develop therapies that are effective.”

 

More Articles

Workplace benefits

March 2014
Tuesday, February 25, 2014

Health care and vacations rule. That’s the consensus from our reader poll on workplace benefits that help retain and recruit employees.


Read more...

Rapid ascent

March 2014
Tuesday, February 25, 2014
IMG 4255-2BY AMY MILSHTEIN

Kelly Dachtler, president of The Clymb, redefines outdoor retail.


Read more...

Closing the gap: Community colleges and workforce training

News
Thursday, March 27, 2014
03.27.14 thumb collegeBY MARY SPILDE | OP-ED CONTRIBUTOR

Community college career, technical and workforce programs present an opportunity to bring business and education together as never before.


Read more...

Green eyeshades in the ivory tower

News
Friday, April 04, 2014
EducationCosts BlogBY ERIC FRUITS

The rapidly rising cost of higher education has left even the smartest researchers and the wonkiest of wonks wondering what’s happening and where’s all that money going. More and more, prospective students—and their families—are asking: Is college worth the cost?


Read more...

How to handle the unexpected

Contributed Blogs
Friday, March 28, 2014
03.28.14 thumb disasterBY TOM COX | OB BLOGGER

The next mysterious (or disastrous) event could be one that you or your team might suddenly need to respond to, probably under intense scrutiny.


Read more...

The 2014 100 Best Companies to Work for in Oregon

News
Friday, February 28, 2014

100best14logo ThumbnailThe 21st annual 100 Best Companies to Work For in Oregon list was announced Thursday night at an awards dinner at the Oregon Convention Center.


Read more...

Q & A with Chuck Eggert

News
Thursday, March 06, 2014
03.06.14 thumb pacfoodsBY HANNAH WALLACE | OB BLOGGER

The founder of Pacific Foods talks about why his company has flown under the radar in Oregon, how saving a family-run chicken hatchery has helped his bottom line and why he thinks organic food is anything but elitist.


Read more...
Oregon Business magazinetitle-sponsored-links-02
SPONSORED LINKS