Home Back Issues February 2013 UO researchers build device to kill off parasitic infections

UO researchers build device to kill off parasitic infections

| Print |  Email
Articles - February 2013
Monday, January 28, 2013

0213 NextBY LINDA BAKER

Parasitic infections are a huge public health problem around the world. Now NemaMetrix, a startup out of the University of Oregon, has built a device to accelerate the development of drugs that kill off or paralyze such parasites, using the lowly roundworm, C. elegans, as a model. The technology takes advantage of the roundworm’s unique pharynx: a heart-like neuromuscular pump that is used in feeding and emits electrical signals that can be monitored, much like an EKG. An array of tiny channels, the device monitors signals in eight roundworms at once while simultaneously administering small quantities of drugs to each one. “If you add a drug and the pharynx stops pumping, it’s a great sign,” says Shawn Lockery, director of the UO Institute of Neuroscience and NemaMetrix co-founder. The company hopes to market the platform, which includes analytic software tools, to pharmaceutical companies as a screening device to identify new antiparasitic drugs. The technology can also be used in toxicology and drug-discovery programs for human metabolic and degenerative diseases, such as Parkinson’s and Huntington’s, says Lockery, noting that 60% of the C. elegans genes are the same as humans’. “Evolution has been very conservative,” he says. 

 

More Articles

True Blood

October 2014
Thursday, September 25, 2014
BY JOE ROJAS-BURKE

Antibiotics really aren’t magic bullets.


Read more...

What I'm Reading

September 2014
Wednesday, August 27, 2014

Kim Ierian, President of Concorde Career Colleges, and Deborah Edward, Executive Director of Business for Culture & the Arts, share their recent reads.


Read more...

November/December Preview: Revenge Forestry

News
Tuesday, October 14, 2014
BY JONATHAN FROCHTZWAJG

Seneca AW46A flare-up in the Elliott Forest raises questions about détente in Oregon’s timber wars.


Read more...

How to add positivity to your team

Contributed Blogs
Friday, September 12, 2014
happy-seo-orlando-clientsBY TOM COX | OB BLOGGER

I often talk about what leaders can do. What about followers? If you’re a team member and you’d like to add positivity to your team, what might you do?


Read more...

Knight Vision

October 2014
Thursday, September 25, 2014
BY VIVIAN MCINERNY

Travis Knight wants to release a movie a year. Can he pull it off?


Read more...

Fast Food Slows Down

September 2014
Tuesday, August 26, 2014
BY KIM MOORE

The ubiquitous fast-food restaurant may be on the decline.


Read more...

Powerlist: Colleges and Universities

September 2014
Wednesday, August 27, 2014
BY KIM MOORE

A conversation about higher education with the presidents of the University of Oregon and Clackamas Community College, followed by September's powerlist.


Read more...
Oregon Business magazinetitle-sponsored-links-02
SPONSORED LINKS