|| Print ||
|Articles - February 2013|
|Monday, January 28, 2013|
BY LINDA BAKER
Parasitic infections are a huge public health problem around the world. Now NemaMetrix, a startup out of the University of Oregon, has built a device to accelerate the development of drugs that kill off or paralyze such parasites, using the lowly roundworm, C. elegans, as a model. The technology takes advantage of the roundworm’s unique pharynx: a heart-like neuromuscular pump that is used in feeding and emits electrical signals that can be monitored, much like an EKG. An array of tiny channels, the device monitors signals in eight roundworms at once while simultaneously administering small quantities of drugs to each one. “If you add a drug and the pharynx stops pumping, it’s a great sign,” says Shawn Lockery, director of the UO Institute of Neuroscience and NemaMetrix co-founder. The company hopes to market the platform, which includes analytic software tools, to pharmaceutical companies as a screening device to identify new antiparasitic drugs. The technology can also be used in toxicology and drug-discovery programs for human metabolic and degenerative diseases, such as Parkinson’s and Huntington’s, says Lockery, noting that 60% of the C. elegans genes are the same as humans’. “Evolution has been very conservative,” he says.
Tuesday, July 08, 2014
BY LINDA BAKER | OB EDITOR
The New Yorker recently published a sharply worded critique of “disruptive innovation,” one of the most widely cited theories in the business world today. The article raises questions about the descriptive value of disruption and innovation — whether the terms are mere buzzwords or actually explain today's extraordinarily complex and fast changing business environment.
Update: We caught up with Portland's Thomas Thurston, who shared his data driven take on the disruption controversy.
Monday, August 18, 2014
Portland is in the middle of another construction boom, with residential and office projects springing up downtown, in the Pearl and Old Town. OB Web Editor Jessica Ridgway documents the new wave.
Wednesday, August 27, 2014
BY JENNIFER MARGULIS
As schools implement more rigorous academic standards, holistic and flexible approaches to K-12 education flourish.
Wednesday, August 13, 2014
BY TOM COX | OB BLOGGER
When I say, “Your Employee is Always Right,” I do not mean “right about the facts,” but rather “right about how they feel” and “right about how they want to be led.”
Tuesday, August 26, 2014
BY DEBRA RINGOLD | OP-ED CONTRIBUTOR
Why has six years become an acceptable investment in public undergraduate education that over-promises and underperforms?
Wednesday, August 27, 2014
BY JESSICA RIDGWAY
How State Representative Julie Parrish (House District 37) balances life between work and play.
Monday, July 14, 2014
BY VIVIAN MCINERNY | OB BLOGGER
Some people think Amazon’s winking eye logo is starting to look like a hoodwink.
|The Private 150: Bigger But Leaner|
|The Perfect Food|
|Powerlist: Staffing Firms|
|Taxis Uber Alles?|
|Halliburton to pay $1.1B to settle lawsuits|
|U.S. eating habits improve, except among poor|
|Google tests drone deliveries|
|Abercrombie to remove logos from most clothing|
|FBI investigates JPMorgan 'cyber-attack'|
|GoPro launches camera dog harnesses|
|Snapchat now worth $10B|
Vigilant enters a New Year with a new president.
How George Fox has become one of Oregon's largest private universities.
Forest Grove sees growth in the burgeoning food and beverage scene.
Lane Powell Shareholder William T. Patton has been appointed to the board of directors for Cascade AIDS Project, an organization that provides educational services and outreach to thousands of Oregonians living with HIV/AIDS.
Fifty-one Lane Powell lawyers were recently selected by their peers for inclusion in The Best Lawyers in America® (Best Lawyers) 2015; of those selected, 23 lawyers are from the Firm’s office in Portland, Oregon.
Barran Liebman is proud to announce that Andrew Schpak, a Partner of the firm, has been named Chair of the American Bar Association’s Young Lawyers Division for the 2014-2015 bar year.