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|Articles - February 2013|
|Monday, January 28, 2013|
BY LINDA BAKER
Parasitic infections are a huge public health problem around the world. Now NemaMetrix, a startup out of the University of Oregon, has built a device to accelerate the development of drugs that kill off or paralyze such parasites, using the lowly roundworm, C. elegans, as a model. The technology takes advantage of the roundworm’s unique pharynx: a heart-like neuromuscular pump that is used in feeding and emits electrical signals that can be monitored, much like an EKG. An array of tiny channels, the device monitors signals in eight roundworms at once while simultaneously administering small quantities of drugs to each one. “If you add a drug and the pharynx stops pumping, it’s a great sign,” says Shawn Lockery, director of the UO Institute of Neuroscience and NemaMetrix co-founder. The company hopes to market the platform, which includes analytic software tools, to pharmaceutical companies as a screening device to identify new antiparasitic drugs. The technology can also be used in toxicology and drug-discovery programs for human metabolic and degenerative diseases, such as Parkinson’s and Huntington’s, says Lockery, noting that 60% of the C. elegans genes are the same as humans’. “Evolution has been very conservative,” he says.
Friday, April 17, 2015
PHOTOS BY JASON E. KAPLAN
The 32nd annual CBC attracted a record number of attendees (11,000) to the Oregon Convention Center.
Friday, March 27, 2015
BY ROBERT MULLIN
A new energy-sharing agreement sparks concerns about independence and collaboration in the region's utility industry.
Thursday, April 30, 2015
BY JACOB PALMER | DIGITAL NEWS EDITOR
Oregonians are scrambling to get their gardens in order for the summer. Here are three tips from landscaping and urban farming expert.
Monday, April 27, 2015
BY KIM MOORE
A conversation with Martha Richards, executive director of the James F. & Marion L. Miller Foundation.
Monday, April 27, 2015
BY JACOB PALMER AND EILEEN GARVIN
A power lunch at Solstice Wood Fire Cafe & Bar.
Thursday, May 21, 2015
BY JASON NORRIS | GUEST BLOGGER
Uncertainty is a part of doing business, whether in through the lens of investment opportunities and risks or the business of running an enterprise.
Wednesday, May 20, 2015
BY KIM MOORE | RESEARCH EDITOR
An earthquake would completely destroy many Oregon businesses, highlighting the urgent need for the private and public sectors to collaborate on shoring up disaster preparedness, said panelists at an Oregon Business breakfast summit today.
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Tourism marketing supports entrepreneurship by attracting visitors to all corners of the state.
Beaverton firm's business intelligence platform rivals that of industry heavyweights.
The Oregon Entrepreneurs Network (OEN) will be presenting its third annual Entrepreneurial Summit on Friday, June 5 at Castaway in Portland, Oregon.
On June 13th Mayor Charlie Hales will attend nonprofit organization Dream Change’s inaugural Love Summit and will introduce one of its keynote speakers, Dan Wieden of Wieden+Kennedy advertising agency.
34 spots for food, 17 places to sip, and 7 sites to choose a brew beckon visitors.