Home Back Issues February 2013 UO researchers build device to kill off parasitic infections

UO researchers build device to kill off parasitic infections

| Print |  Email
Articles - February 2013
Monday, January 28, 2013

0213 NextBY LINDA BAKER

Parasitic infections are a huge public health problem around the world. Now NemaMetrix, a startup out of the University of Oregon, has built a device to accelerate the development of drugs that kill off or paralyze such parasites, using the lowly roundworm, C. elegans, as a model. The technology takes advantage of the roundworm’s unique pharynx: a heart-like neuromuscular pump that is used in feeding and emits electrical signals that can be monitored, much like an EKG. An array of tiny channels, the device monitors signals in eight roundworms at once while simultaneously administering small quantities of drugs to each one. “If you add a drug and the pharynx stops pumping, it’s a great sign,” says Shawn Lockery, director of the UO Institute of Neuroscience and NemaMetrix co-founder. The company hopes to market the platform, which includes analytic software tools, to pharmaceutical companies as a screening device to identify new antiparasitic drugs. The technology can also be used in toxicology and drug-discovery programs for human metabolic and degenerative diseases, such as Parkinson’s and Huntington’s, says Lockery, noting that 60% of the C. elegans genes are the same as humans’. “Evolution has been very conservative,” he says. 

 

More Articles

The 2014 List: The Top 33 Large Companies to Work, For in Oregon

March 2014
Thursday, February 27, 2014

100best14logoWebOur 100 Best Companies project turned 21 this year, so pop open the Champagne. Our latest survey gives us plenty to cheer.

 


Read more...

Making faces

News
Thursday, February 20, 2014
02.20.14 Thumbnail ModelsBY VIVIAN MCINERNY | OB BLOGGER

As retailers consolidate and newspapers fold, the business of modeling shifts to ad agencies, apparel companies and new media.


Read more...

Q & A with Chuck Eggert

News
Thursday, March 06, 2014
03.06.14 thumb pacfoodsBY HANNAH WALLACE | OB BLOGGER

The founder of Pacific Foods talks about why his company has flown under the radar in Oregon, how saving a family-run chicken hatchery has helped his bottom line and why he thinks organic food is anything but elitist.


Read more...

The 2014 List: The Top 33 Small Companies to Work, For in Oregon

March 2014
Thursday, February 27, 2014

100best14logoWebOur 100 Best Companies project turned 21 this year, so pop open the Champagne. Our latest survey gives us plenty to cheer.

 


Read more...

Branching out

March 2014
Tuesday, February 25, 2014
DSC04185BY LINDA BAKER

A blueberry bush is a blueberry bush — except when it’s a blueberry tree.


Read more...

How to boost web traffic

News
Thursday, April 10, 2014
BY JESSICA RIDGWAY  | OB WEB EDITOR

04.10.14 thumb seo-trafficSEMpdx hosted a workshop this week for entrepreneurs, website developers and others interested in search engine optimization (SEO).  Here are a few tips and tricks aimed at bumping up your search engine rankings.


Read more...

Buy the book

News
Tuesday, March 25, 2014
2 03.25.14 thumb bookshopBY VIVIAN MCINERNY | OB BLOGGER

Oregon is home not only to many fine writers but also several accomplished small publishers.


Read more...
Oregon Business magazinetitle-sponsored-links-02
SPONSORED LINKS