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|Friday, May 01, 2009|
From stronger teeth to sharper eyes to a rewired brain, Oregon innovators are finding ways to keep us living longer and better.
BY JON BELL
Who: Greta Binford, assistant professor of biology
Who: SAM Medical Products
Who: Chrissa Kioussi, assistant professor of pharmacology
Who: Bend Research
What: Drug delivery technology
You can cross your heart and hope to die, but thanks to scientists at Bend Research, you may never have to stick a needle in your eye — at least not to deliver drugs for glaucoma.
“As you can imagine, that’s not a lot of fun,” says Rod Ray, chief executive officer of the 34-year-old Bend medical company.
Among its other innovations, Bend Research is developing new technologies for administering drugs to the eyes, including drops that contain powerful medicine in nanoparticle form. Ray says researchers there have also been working on ways to make drugs more soluble and to target them to specific sites in the body. The latter would not only reduce the amount of drug needed, but would also help ensure that, say, cancer drugs would head straight for a tumor.
“That technology is a really important one for fighting cancer,” says Ray.
Bend Research, which developed the popular one-dose antibiotic Zmax, recently left a 14-year exclusive partnership with the pharmaceutical giant Pfizer, and is currently harvesting new relationships with biotech and drug companies around the world.
Ray says he sees the company continuing to make advances in the pharmaceutical realm and dabbling in the world of diagnostics. A possible next step: a new and better cholesterol test.
Who: Scott Frey, psychology professor
What: Brain adaptation research
Where: University of Oregon, Eugene
If Scott Frey is right about the human brain, we may be in for some monumental shifts in the treatment of everything from strokes to spinal cord damage.
Studying a handful of amputees who’ve been “cured” via hand transplants, Frey has learned that the brain is a mighty organizer. Not only does it reorganize itself after the limb is lost, but it then “re-reorganizes” itself when a new limb is attached. Feeling comes back and the brain begins processing signals from the new hand in the same region it did for the original hand.
“Our case presents the most compelling case that the brain can go back to the way it was,” Frey says.
The broader implication could theoretically mean that the brain would be able to rewire itself in, say, a paralyzed patient whose damaged spinal cord has been repaired by stem cells. Damage from strokes, concussive head injuries and diseases such as multiple sclerosis might also someday be abated with a better understanding of how the brain adapts.
Frey’s next wave of related research, funded by the Department of Defense, finds him recruiting arm and hand amputees to learn more about the brain’s role in phantom pain and the nearly 50% of upper limb amputees who reject prostheses.
“I would like to see us get a better understanding of these basic brain changes,” he says, “and the extent to which they can be reversed.”
Who: Neda Shamie, MD
What: Cataract and corneal surgery
Where: Legacy’s Devers Eye Institute, Portland
Oregon’s the right location for snowy mountains, microbrews and, apparently, afflictions of the eye.
“Oregon is a great place to be if you have an eye disease,” says Neda Shamie, a corneal and laser refractive surgeon at Legacy Good Samaritan Hospital’s Devers Eye Institute.
Shamie is one of Devers’ surgeons who specializes in some of the latest and greatest procedures out there. One example: advanced intraocular lens surgery for cataracts, where surgeons implant premium lenses that restore vision to near 20-20 and usually render reading glasses unnecessary.
But where Shamie and Devers really shine is in the realm of the cornea. Her colleague, Mark Terry, revolutionized cornea transplants 10 years ago with a technique that replaces only the damaged layer of the cornea, not the entire thickness as had been standard practice. Shamie herself has done more than 100 of those surgeries since joining Devers in 2006.
The institute is also one of the only facilities in Oregon to offer artificial cornea implanting, a new option for high-risk patients who’ve had multiple regular implants fail.
“There are books that can be written on what’s to come,” says Shamie.
Wednesday, September 30, 2015
BY LINDA BAKER | EDITOR
The media coverage about Pope Francis must have put me in a Biblical frame of mind. Because after touring the latest phase of the South Waterfront development, a mind boggling 1.5 million square feet of office and retail space that will spring up north of the aerial tram over the next few years, I couldn’t stop thinking about the massive project as a modern day creation story.
Friday, October 02, 2015
BY KIM MOORE
Our intrepid (and expecting) research editor finds the child care search involves long waiting lists, costly fees and no certainty of securing a place before she goes back to work.
Thursday, October 01, 2015
PHOTOS BY JASON E. KAPLAN
Images from the big 2015 celebration of worker-friendly organizations that make a difference.
Wednesday, August 26, 2015
BY KIM MOORE AND LINDA BAKER
Child care in Oregon is expensive and hard to find. We delved into the numbers and talked to a few executives and managers about day care costs, accessibility and work-life balance.
Monday, October 05, 2015
VIDEO BY JESSE LARSON
Profiling some of the organizations featured in the 2015 list.
Wednesday, August 19, 2015
BY LINDA WESTON
In 1996, after a 17-year career in the destination marketing industry, where I gained national standing as the CEO of the Convention & Visitors Association of Lane County, I was recruited by the founders of a new professional basketball league for women. The American Basketball League (ABL) hoped to leverage the success of the 1996 USA women’s national team at the Atlanta Olympics — much like USA Soccer is now leveraging the U.S. Women’s National Team’s victory in the World Cup. The ABL wanted a team in Portland, and they wanted me to be its general manager.
Wednesday, September 30, 2015
BY KIM MOORE
Oregon Business magazine’s seventh annual 100 Best Nonprofits to Work For project attracted more than 150 nonprofits from around the state from a variety of sectors, including social services and environmental advocacy. More than 5,000 employees and volunteers filled out the survey, rating their satisfaction with work environment, mission and goals, career development and learning, benefits and compensation, and management and communications.
|The List: 100 Best Nonprofits to Work For in Oregon|
|Run, Nick, Run|
|100 Best Nonprofits: Working for equality inside and out|
|One Tough Mayor|
|Keep Pendleton Weird|
|Cream of the Crop|
|Portland State campus security to carry guns|
|Twitter's Steve Jobs?|
|American Apparel files for Ch. 11|
|Hiring report disappoints|
|Phil Knight memoir: Coming spring 2016|
|2 out of 5 millennials pay for their news|
|Oregon's graying workforce|
Wage gaps and workforce shortages are threatening the quality of care and supports to Oregonians with intellectual and developmental disabilities. Who’s caring for those who care for our most vulnerable residents?
Engaging employees and customers along the way.
After first visiting as tourists, entrepreneurs relocate to Oregon and spur economic growth.
Hans N. Hugglerhas joined Lane Powell as an Attorney in the Litigation Practice Group, where he will focus his practice on complex litigation.
Over 300 attendees will gather to learn from 50+ regional leaders pushing the sustainability needle forward. GoGreen Portland offers a distinct platform of bringing people together across industries and sectors to build viable networks and cross-pollinate best practices throughout the regional business community.
Are you planning a meeting, party, gala, fundraiser, holiday party, golf tournament, retirement party, team building or birthday? You won’t want to miss this show to get hundreds of great ideas!