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|Friday, May 01, 2009|
From stronger teeth to sharper eyes to a rewired brain, Oregon innovators are finding ways to keep us living longer and better.
BY JON BELL
Who: Greta Binford, assistant professor of biology
Who: SAM Medical Products
Who: Chrissa Kioussi, assistant professor of pharmacology
Who: Bend Research
What: Drug delivery technology
You can cross your heart and hope to die, but thanks to scientists at Bend Research, you may never have to stick a needle in your eye — at least not to deliver drugs for glaucoma.
“As you can imagine, that’s not a lot of fun,” says Rod Ray, chief executive officer of the 34-year-old Bend medical company.
Among its other innovations, Bend Research is developing new technologies for administering drugs to the eyes, including drops that contain powerful medicine in nanoparticle form. Ray says researchers there have also been working on ways to make drugs more soluble and to target them to specific sites in the body. The latter would not only reduce the amount of drug needed, but would also help ensure that, say, cancer drugs would head straight for a tumor.
“That technology is a really important one for fighting cancer,” says Ray.
Bend Research, which developed the popular one-dose antibiotic Zmax, recently left a 14-year exclusive partnership with the pharmaceutical giant Pfizer, and is currently harvesting new relationships with biotech and drug companies around the world.
Ray says he sees the company continuing to make advances in the pharmaceutical realm and dabbling in the world of diagnostics. A possible next step: a new and better cholesterol test.
Who: Scott Frey, psychology professor
What: Brain adaptation research
Where: University of Oregon, Eugene
If Scott Frey is right about the human brain, we may be in for some monumental shifts in the treatment of everything from strokes to spinal cord damage.
Studying a handful of amputees who’ve been “cured” via hand transplants, Frey has learned that the brain is a mighty organizer. Not only does it reorganize itself after the limb is lost, but it then “re-reorganizes” itself when a new limb is attached. Feeling comes back and the brain begins processing signals from the new hand in the same region it did for the original hand.
“Our case presents the most compelling case that the brain can go back to the way it was,” Frey says.
The broader implication could theoretically mean that the brain would be able to rewire itself in, say, a paralyzed patient whose damaged spinal cord has been repaired by stem cells. Damage from strokes, concussive head injuries and diseases such as multiple sclerosis might also someday be abated with a better understanding of how the brain adapts.
Frey’s next wave of related research, funded by the Department of Defense, finds him recruiting arm and hand amputees to learn more about the brain’s role in phantom pain and the nearly 50% of upper limb amputees who reject prostheses.
“I would like to see us get a better understanding of these basic brain changes,” he says, “and the extent to which they can be reversed.”
Who: Neda Shamie, MD
What: Cataract and corneal surgery
Where: Legacy’s Devers Eye Institute, Portland
Oregon’s the right location for snowy mountains, microbrews and, apparently, afflictions of the eye.
“Oregon is a great place to be if you have an eye disease,” says Neda Shamie, a corneal and laser refractive surgeon at Legacy Good Samaritan Hospital’s Devers Eye Institute.
Shamie is one of Devers’ surgeons who specializes in some of the latest and greatest procedures out there. One example: advanced intraocular lens surgery for cataracts, where surgeons implant premium lenses that restore vision to near 20-20 and usually render reading glasses unnecessary.
But where Shamie and Devers really shine is in the realm of the cornea. Her colleague, Mark Terry, revolutionized cornea transplants 10 years ago with a technique that replaces only the damaged layer of the cornea, not the entire thickness as had been standard practice. Shamie herself has done more than 100 of those surgeries since joining Devers in 2006.
The institute is also one of the only facilities in Oregon to offer artificial cornea implanting, a new option for high-risk patients who’ve had multiple regular implants fail.
“There are books that can be written on what’s to come,” says Shamie.
Wednesday, February 25, 2015
BY JASON NORRIS, CFA | OB GUEST BLOGGER
Pets.com, GeoCities, eToys, and WorldCom … blasts-from-the-past that all signify the late 1990s Internet bubble. Yet we believe the dynamics of the market, specifically in technology stocks, are much different today than it was during the late 1990s.
Thursday, March 26, 2015
BY JACOB PALMER
Enjoying a power lunch at Court Street Dairy Lunch in Salem.
Tuesday, January 27, 2015
BY KIM MOORE
Robin Anderson, dean of the Pamplin School of Business, University of Portland: "You need people who are comfortable leading in ambiguity."
Friday, March 13, 2015
BY JACOB PALMER | OB DIGITAL NEWS EDITOR
Ten startups have secured venture capital, angel or seed funding in 2015.
Thursday, February 26, 2015
BY KIM MOORE | OB RESEARCH EDITOR
Employment in Oregon is almost back up to prerecession levels — and employers are having to work harder to entice talented staff to join their ranks. This year’s 100 Best Companies to Work For in Oregon project showcases the kind of quality workplaces that foster happy employees.
Monday, February 23, 2015
BY JESSICA RIDGWAY | OB CONTRIBUTOR
Live, Work, Play: Catching up with Chris Johnson.
Wednesday, February 25, 2015
BY LINDA BAKER | OB EDITOR
The big news at Oregon Business is we’re getting a ping pong table. After reading the descriptions of the 2015 100 Best Companies to Work For in Oregon, a disproportionate number of which feature table tennis in the office, I decided it was time to bring our own workplace into the 21st century. It was a tough call, but it’s lonely at the top, and someone has to make the hard decisions.
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|On the Brink|
|Thy neighbor's house|
|Norwegian Air tweaks cockpit rules after Germanwings crash|
|Federal Consumer Agency addresses payday loans|
|Slave-caught seafood sold in America|
|Heinz, Kraft merge|
|West Coast lawmakers want earthquake warning funding|
|Online network plans to charge subscribers for early access to popular YouTube videos|
|Wyoming — not Florida — is the best state in which to retire|
Generations of students and graduates have been plagued by the question: What is my true calling in life? Four alumni from Corban University’s Hoff School of Business who graduated in different decades say the school helped them find the answer by giving them a practical, well-rounded education.
It’s happening whether anyone’s ready or not. Businesses here in Oregon and across the U.S. are already experiencing the effects of the largest generational shift in recent history, and these changing tides will impact every level of the workplace — from a company’s executive leadership to its cultural core.
Success stories spotlight meaningful career opportunities in Oregon's diverse and lucrative tourism industry.
Registration is now open for Portland Business Alliance’s Annual Meeting, one of the largest business gatherings in Portland each year.
The Commission helps to advance the professionalism, equality and efficiency of Oregon's judicial branch of government.
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