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|Saturday, December 01, 2007|
It’s a tricky thing to talk up a mouse without getting cheesy. But this little guy, by all appearances a normal rodent, has a human liver inside of it, making it a real-life mighty mouse worth at least five grand. Markus Grompe of the Oregon Stem Cell Center at Oregon Health & Science University is breeding more of this star in hopes of revolutionizing the way drugs are tested. The mouse’s liver is infected with disease and then healthy human liver cells are transplanted into it; these human cells thrive until the liver is only 10% mouse. The new liver allows the mice to metabolize and excrete medications like a human. Pharmaceutical companies testing medication toxicity and searching for disease cures are interested because testing on this mouse is like testing on real human liver cells, which are hard to come by. Previous technology only allowed for an inconsequential number of human cells in mice, and a more recent Japanese version can’t control the liver disease or stop healthy mouse liver cells from regenerating. Those mice have shorter life spans and are difficult to breed, which makes Grompe optimistic that he’s developed a big seller. With the Japanese mice selling for $5,000 each, Grompe could be holding a small, furry fortune in his hands. AMBER NOBE
Wednesday, January 14, 2015
BY NISHANT BHAJARIA | OP-ED CONTRIBUTOR
Startups in the growth phase are associated with a fresh infusion of capital — human and financial — a curiosity factor and products to disrupt the market and drive demand. Portland’s economy gives off the same aroma.
Tuesday, February 24, 2015
BY KIM MOORE | OB RESEARCH EDITOR
A conversation with Donna Earley, director of sales and marketing for the Salem Convention Center.
Friday, February 27, 2015
VIDEO: 2015 100 Best Companies to work for in Oregon
Tuesday, February 17, 2015
BY TAMSEN LEACHMAN | OB GUEST CONTRIBUTOR
It is important to understand the EEOC’s priorities, and ensure that your leadership understands the shifting expectations of regulators and the heightened standards to which you (and they) may be held.
Monday, January 26, 2015
BY KIM MOORE
After more than a decade of wrangling, construction on a convention center hotel in Portland is slated to start this summer. But debate over project financing continues.
Wednesday, January 14, 2015
BY JACOB PALMER | OB DIGITAL NEWS EDITOR
Portland's cab companies urged city hall for consideration as officials weigh new rules for Uber and other ridesharing companies.
Friday, January 23, 2015
BY LINDA BAKER | OB EDITOR
The Northwest Environmental Business Council previews the 2015 legislative agenda as Hatch Oregon celebrates Oregon's new community crowdfunding rules.
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Generations of students and graduates have been plagued by the question: What is my true calling in life? Four alumni from Corban University’s Hoff School of Business who graduated in different decades say the school helped them find the answer by giving them a practical, well-rounded education.
It’s happening whether anyone’s ready or not. Businesses here in Oregon and across the U.S. are already experiencing the effects of the largest generational shift in recent history, and these changing tides will impact every level of the workplace — from a company’s executive leadership to its cultural core.
Success stories spotlight meaningful career opportunities in Oregon's diverse and lucrative tourism industry.
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The Oregon Chapter of the Society for Marketing Professional Services, will be hosting it’s Annual Dinner and Keynote event on March 12, 2015. The evening promises to be memorable, with this years Keynote, Christine McKinley.
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