Next: an anti-malarial drug

| Print |  Email
Sunday, February 01, 2009
mosquito.jpg

In the race to cure malaria, the devastating disease that claims 1 million lives each year, every development is critical. The deadliest strain has grown increasingly resistant to chloroquine, the safest and cheapest anti-malarial drug available. The parasite that carries the virus has developed a “siphon” to purge the drug from itself. But instead of developing a new drug, a lengthy and costly process, Portland State University professor David Peyton and his research team at DesignMedix are re-engineering the original. These “reversed chloroquines” block the parasite’s siphon, killing the parasite. Some of these molecules are 10 times more effective than chloroquine alone, decreasing the required dosage significantly. Smaller doses could mean fewer side effects and lower manufacturing costs, Peyton says. The drug is expected to move to human trials in the next two to three years. Peyton sees the eradication of the disease as critical to the health of women and children, and for the health of malaria-stricken countries. “What the world needs now,” Peyton says, “is very good, very safe, very cheap anti-malarial drugs.”

NICOLE STORMBERG



Have an opinion? E-mail This e-mail address is being protected from spambots. You need JavaScript enabled to view it
 

More Articles

Political theater

News
Wednesday, January 07, 2015
0107-orbizplansum14-thumbBY LINDA BAKER | OB EDITOR

The Oregon Business Plan Leadership Summit drew more than 1,000 people to the Oregon Convention Center yesterday.


Read more...

LEED for weed

News
Wednesday, January 28, 2015
012815-potcarbon-thumbBY LINDA BAKER | OB EDITOR

What is the impact of the legal pot industry on carbon emissions? An NEBC energy forum breakfast makes the case for taking the new industry’s emissions impacts seriously.


Read more...

Editor's Letter: Power Play

January-Powerbook 2015
Thursday, December 11, 2014

There’s a fascinating article in the December issue of the Harvard Business Review about a profound power shift taking place in business and society. It’s a long read, but the gist revolves around the tension between “old power” and “new power” as a driver of transformation.


Read more...

The city as startup

Guest Blog
Wednesday, January 14, 2015
011415 citystartup-thumbBY NISHANT BHAJARIA | OP-ED CONTRIBUTOR

Startups in the growth phase are associated with a fresh infusion of capital — human and financial — a curiosity factor and products to disrupt the market and drive demand. Portland’s economy gives off the same aroma.


Read more...

Corner Office: Timothy Mitchell

January-Powerbook 2015
Saturday, December 13, 2014

A look-in on the life of Norris & Stevens' president, plus an abridged Powerlist for the best commercial real estate firms.


Read more...

Finding a Balance

Contributed Blogs
Thursday, January 29, 2015
012915-passinvst-thumbBY JASON NORRIS | OB GUEST BLOGGER

Active vs. passive investing: what you need to know.


Read more...

Live, Work, Play: Amen Teter

February 2015
Tuesday, January 27, 2015
BY JACOB PALMER

Catching up with Amen Teter, Portland-based global director of action sports for Octagon Olympics & Action sports talent agency.


Read more...
Oregon Business magazinetitle-sponsored-links-02
SPONSORED LINKS